A New Safety Concern for Glaucoma Treatment Demonstrated by Mass Spectrometry Imaging of Benzalkonium Chloride Distribution in the Eye, an Experimental Study in Rabbits

We investigated in a rabbit model, the eye distribution of topically instilled benzalkonium_(BAK) chloride a commonly used preservative in eye drops using mass spectrometry imaging. Three groups of three New Zealand rabbits each were used: a control one without instillation, one receiving 0.01%BAK t...

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Detalles Bibliográficos
Autores principales: Brignole-Baudouin, Françoise, Desbenoit, Nicolas, Hamm, Gregory, Liang, Hong, Both, Jean-Pierre, Brunelle, Alain, Fournier, Isabelle, Guerineau, Vincent, Legouffe, Raphael, Stauber, Jonathan, Touboul, David, Wisztorski, Maxence, Salzet, Michel, Laprevote, Olivier, Baudouin, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507684/
https://www.ncbi.nlm.nih.gov/pubmed/23209668
http://dx.doi.org/10.1371/journal.pone.0050180

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