PA from an H5N1 highly pathogenic avian influenza virus activates viral transcription and replication and induces apoptosis and interferon expression at an early stage of infection

BACKGROUND: Although gene exchange is not likely to occur freely, reassortment between the H5N1 highly pathogenic avian influenza virus (HPAIV) and currently circulating human viruses is a serious concern. The PA polymerase subunit of H5N1 HPAIV was recently reported to activate the influenza replic...

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Detalles Bibliográficos
Autores principales: Wang, Qiang, Zhang, Shijian, Jiang, Hongbing, Wang, Jinlan, Weng, Leiyun, Mao, Yingying, Sekiguchi, Satoshi, Yasui, Fumihiko, Kohara, Michinori, Buchy, Philippe, Deubel, Vincent, Xu, Ke, Sun, Bing, Toyoda, Tetsuya
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507744/
https://www.ncbi.nlm.nih.gov/pubmed/22681768
http://dx.doi.org/10.1186/1743-422X-9-106

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