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Euchromatin islands in large heterochromatin domains are enriched for CTCF binding and differentially DNA-methylated regions
BACKGROUND: The organization of higher order chromatin is an emerging epigenetic mechanism for understanding development and disease. We and others have previously observed dynamic changes during differentiation and oncogenesis in large heterochromatin domains such as Large Organized Chromatin K (ly...
Autores principales: | Wen, Bo, Wu, Hao, Loh, Yuin-Han, Briem, Eirikur, Daley, George Q, Feinberg, Andrew P |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507770/ https://www.ncbi.nlm.nih.gov/pubmed/23102236 http://dx.doi.org/10.1186/1471-2164-13-566 |
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