Fission Yeast 26S Proteasome Mutants Are Multi-Drug Resistant Due to Stabilization of the Pap1 Transcription Factor

Here we report the result of a genetic screen for mutants resistant to the microtubule poison methyl benzimidazol-2-yl carbamate (MBC) that were also temperature sensitive for growth. In total the isolated mutants were distributed in ten complementation groups. Cloning experiments revealed that most...

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Detalles Bibliográficos
Autores principales: Penney, Mary, Samejima, Itaru, Wilkinson, Caroline R., McInerny, Christopher J., Mathiassen, Søs G., Wallace, Mairi, Toda, Takashi, Hartmann-Petersen, Rasmus, Gordon, Colin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507774/
https://www.ncbi.nlm.nih.gov/pubmed/23209828
http://dx.doi.org/10.1371/journal.pone.0050796

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507774/
https://www.ncbi.nlm.nih.gov/pubmed/23209828
http://dx.doi.org/10.1371/journal.pone.0050796

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