High-Mobility Group Box-1 Induces Proinflammatory Cytokines Production of Kupffer Cells through TLRs-Dependent Signaling Pathway after Burn Injury

Kupffer cells (KCs) were a significant source of cytokine release during the early stage of severe burns. High mobility group box protein 1 (HMGB1) was recently identified as a new type of proinflammatory cytokine. The ability of HMGB1 to generate inflammatory responses after burn trauma has not bee...

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Detalles Bibliográficos
Autores principales: Chen, Xu-Lin, Sun, Li, Guo, Feng, Wang, Fei, Liu, Sheng, Liang, Xun, Wang, Ren-Su, Wang, Yong-Jie, Sun, Ye-Xiang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507775/
https://www.ncbi.nlm.nih.gov/pubmed/23209806
http://dx.doi.org/10.1371/journal.pone.0050668

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