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Two glutamic acid residues in the DNA-binding domain are engaged in the release of STAT1 dimers from DNA

BACKGROUND: In interferon-γ-stimulated cells, the dimeric transcription factor STAT1 (signal transducer and activator of transcription 1) recognizes semi-palindromic motifs in the promoter regions of cytokine-driven target genes termed GAS (gamma-activated sites). However, the molecular steps that f...

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Detalles Bibliográficos
Autores principales:	Koch, Verena, Staab, Julia, Ruppert, Volker, Meyer, Thomas
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507856/ https://www.ncbi.nlm.nih.gov/pubmed/22920460 http://dx.doi.org/10.1186/1471-2121-13-22

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