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Quantification of Regulatory T Cells in Septic Patients by Real-Time PCR–Based Methylation Assay and Flow Cytometry
During sepsis, a relative increase of regulatory T (Treg) cells has been reported. Its persistence is associated with lymphocyte anergy, immunoparalysis and a poor prognosis. Currently, an exact quantification of human Treg cells based on protein expression of marker molecules is ambiguous, as these...
Autores principales: | Tatura, Roman, Zeschnigk, Michael, Adamzik, Michael, Probst-Kepper, Michael, Buer, Jan, Kehrmann, Jan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507919/ https://www.ncbi.nlm.nih.gov/pubmed/23209626 http://dx.doi.org/10.1371/journal.pone.0049962 |
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