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GH Mediates Exercise-Dependent Activation of SVZ Neural Precursor Cells in Aged Mice

Here we demonstrate, both in vivo and in vitro, that growth hormone (GH) mediates precursor cell activation in the subventricular zone (SVZ) of the aged (12-month-old) brain following exercise, and that GH signaling stimulates precursor activation to a similar extent to exercise. Our results reveal...

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Detalles Bibliográficos
Autores principales: Blackmore, Daniel G., Vukovic, Jana, Waters, Michael J., Bartlett, Perry F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3507946/
https://www.ncbi.nlm.nih.gov/pubmed/23209615
http://dx.doi.org/10.1371/journal.pone.0049912