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Safety and efficacy of personal care products containing colloidal oatmeal
BACKGROUND: Colloidal oatmeal is a natural ingredient used in the formulation of a range of personal care products for relief of skin dryness and itchiness. It is also used as an adjunctive product in atopic dermatitis. The safety of personal care products used on vulnerable skin is of particular im...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508548/ https://www.ncbi.nlm.nih.gov/pubmed/23204849 http://dx.doi.org/10.2147/CCID.S31375 |
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author | Criquet, Maryline Roure, Romain Dayan, Liliane Nollent, Virginie Bertin, Christiane |
author_facet | Criquet, Maryline Roure, Romain Dayan, Liliane Nollent, Virginie Bertin, Christiane |
author_sort | Criquet, Maryline |
collection | PubMed |
description | BACKGROUND: Colloidal oatmeal is a natural ingredient used in the formulation of a range of personal care products for relief of skin dryness and itchiness. It is also used as an adjunctive product in atopic dermatitis. The safety of personal care products used on vulnerable skin is of particular importance and the risk of developing further skin irritations and/or allergies should be minimized. METHODS: In a series of studies, we tested the safety of personal care products containing oatmeal (creams, cleansers, lotions) by assessing their irritant/allergenic potential on repeat insult patch testing, in safety-in-use and ocular studies using subjects with nonsensitive and sensitive skin. We also tested the skin moisturizing and repair properties of an oatmeal-containing skin care product for dry skin. RESULTS: We found that oatmeal-containing personal care products had very low irritant potential as well as a very low allergenic sensitization potential. Low-level reactions were documented in 1.0% of subjects during the induction phase of repeat insult patch testing; one of 2291 subjects developed a persistent but doubtful low-level reaction involving edema during the challenge phase in repeat insult patch testing. No allergies were reported by 80 subjects after patch testing after in-use application. Sustained skin moisturizing was documented in subjects with dry skin that lasted up to 2 weeks after product discontinuation. CONCLUSION: Our results demonstrate that colloidal oatmeal is a safe and effective ingredient in personal care products. No allergies were reported by consumers of 445,820 products sold during a 3-year period. |
format | Online Article Text |
id | pubmed-3508548 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2012 |
publisher | Dove Medical Press |
record_format | MEDLINE/PubMed |
spelling | pubmed-35085482012-11-30 Safety and efficacy of personal care products containing colloidal oatmeal Criquet, Maryline Roure, Romain Dayan, Liliane Nollent, Virginie Bertin, Christiane Clin Cosmet Investig Dermatol Expert Opinion BACKGROUND: Colloidal oatmeal is a natural ingredient used in the formulation of a range of personal care products for relief of skin dryness and itchiness. It is also used as an adjunctive product in atopic dermatitis. The safety of personal care products used on vulnerable skin is of particular importance and the risk of developing further skin irritations and/or allergies should be minimized. METHODS: In a series of studies, we tested the safety of personal care products containing oatmeal (creams, cleansers, lotions) by assessing their irritant/allergenic potential on repeat insult patch testing, in safety-in-use and ocular studies using subjects with nonsensitive and sensitive skin. We also tested the skin moisturizing and repair properties of an oatmeal-containing skin care product for dry skin. RESULTS: We found that oatmeal-containing personal care products had very low irritant potential as well as a very low allergenic sensitization potential. Low-level reactions were documented in 1.0% of subjects during the induction phase of repeat insult patch testing; one of 2291 subjects developed a persistent but doubtful low-level reaction involving edema during the challenge phase in repeat insult patch testing. No allergies were reported by 80 subjects after patch testing after in-use application. Sustained skin moisturizing was documented in subjects with dry skin that lasted up to 2 weeks after product discontinuation. CONCLUSION: Our results demonstrate that colloidal oatmeal is a safe and effective ingredient in personal care products. No allergies were reported by consumers of 445,820 products sold during a 3-year period. Dove Medical Press 2012-11-08 /pmc/articles/PMC3508548/ /pubmed/23204849 http://dx.doi.org/10.2147/CCID.S31375 Text en © 2012 Criquet et al, publisher and licensee Dove Medical Press Ltd. This is an Open Access article which permits unrestricted noncommercial use, provided the original work is properly cited. |
spellingShingle | Expert Opinion Criquet, Maryline Roure, Romain Dayan, Liliane Nollent, Virginie Bertin, Christiane Safety and efficacy of personal care products containing colloidal oatmeal |
title | Safety and efficacy of personal care products containing colloidal oatmeal |
title_full | Safety and efficacy of personal care products containing colloidal oatmeal |
title_fullStr | Safety and efficacy of personal care products containing colloidal oatmeal |
title_full_unstemmed | Safety and efficacy of personal care products containing colloidal oatmeal |
title_short | Safety and efficacy of personal care products containing colloidal oatmeal |
title_sort | safety and efficacy of personal care products containing colloidal oatmeal |
topic | Expert Opinion |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508548/ https://www.ncbi.nlm.nih.gov/pubmed/23204849 http://dx.doi.org/10.2147/CCID.S31375 |
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