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Skeletal muscle molecular alterations precede whole-muscle dysfunction in NYHA Class II heart failure patients
BACKGROUND: Heart failure (HF), a debilitating disease in a growing number of adults, exerts structural and neurohormonal changes in both cardiac and skeletal muscles. However, these alterations and their affected molecular pathways remain uncharacterized. Disease progression is known to transform s...
Autores principales: | Godard, Michael P, Whitman, Samantha A, Song, Yao-Hua, Delafontaine, Patrice |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove Medical Press
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508558/ https://www.ncbi.nlm.nih.gov/pubmed/23204842 http://dx.doi.org/10.2147/CIA.S37879 |
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