Cargando…

Altered CD38/Cyclic ADP-Ribose Signaling Contributes to the Asthmatic Phenotype

CD38 is a transmembrane glycoprotein expressed in airway smooth muscle cells. The enzymatic activity of CD38 generates cyclic ADP-ribose from β-NAD. Cyclic ADP-ribose mobilizes intracellular calcium during activation of airway smooth muscle cells by G-protein-coupled receptors through activation of...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jude, Joseph A., Dileepan, Mythili, Panettieri, Reynold A., Walseth, Timothy F., Kannan, Mathur S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508580/ https://www.ncbi.nlm.nih.gov/pubmed/23213344 http://dx.doi.org/10.1155/2012/289468

Ejemplares similares

MicroRNA-708 regulates CD38 expression through signaling pathways JNK MAP kinase and PTEN/AKT in human airway smooth muscle cells
por: Dileepan, Mythili, et al.
Publicado: (2014)

CD38–Cyclic ADP-Ribose Signal System in Physiology, Biochemistry, and Pathophysiology
por: Takasawa, Shin
Publicado: (2022)

Regulation of the cd38 promoter in human airway smooth muscle cells by TNF-α and dexamethasone
por: Tirumurugaan, Krishnaswamy G, et al.
Publicado: (2008)

Inhibition of CD38/Cyclic ADP-ribose Pathway Protects Rats against Ropivacaine-induced Convulsion
por: Zou, Yu, et al.
Publicado: (2017)

Downregulation of the Cd38-Cyclic ADP-Ribose Signaling in Cardiomyocytes by Intermittent Hypoxia via Pten Upregulation
por: Takasawa, Shin, et al.
Publicado: (2022)

MicroRNA Mediated Chemokine Responses in Human Airway Smooth Muscle Cells
por: Dileepan, Mythili, et al.
Publicado: (2016)

Cyclic Adenosine 5′-Diphosphate Ribose Analogs without a “Southern” Ribose Inhibit ADP-ribosyl Cyclase–Hydrolase CD38
por: Swarbrick, Joanna M., et al.
Publicado: (2014)

Pancreatic β-Cell Death, Regeneration and Insulin Secretion: Roles of Poly(ADP-Ribose) Polymerase and Cyclic ADP-Ribose
por: Takasawa, Shin, et al.
Publicado: (2002)

Molecular Bases of Catalysis and ADP-Ribose Preference of Human Mn(2+)-Dependent ADP-Ribose/CDP-Alcohol Diphosphatase and Conversion by Mutagenesis to a Preferential Cyclic ADP-Ribose Phosphohydrolase
por: Cabezas, Alicia, et al.
Publicado: (2015)

Specific cyclic ADP-ribose phosphohydrolase obtained by mutagenic engineering of Mn(2+)-dependent ADP-ribose/CDP-alcohol diphosphatase
por: Ribeiro, João Meireles, et al.
Publicado: (2018)

Cyclic ADP-Ribose and Heat Regulate Oxytocin Release via CD38 and TRPM2 in the Hypothalamus during Social or Psychological Stress in Mice
por: Zhong, Jing, et al.
Publicado: (2016)

‘Click cyclic ADP-ribose’: a neutral second messenger mimic
por: Swarbrick, Joanna M., et al.
Publicado: (2014)

8-Bromo-cyclic inosine diphosphoribose: towards a selective cyclic ADP-ribose agonist
por: Kirchberger, Tanja, et al.
Publicado: (2009)

Design and Synthesis of Cyclic ADP-4-Thioribose as a Stable Equivalent of Cyclic ADP-Ribose, a Calcium Ion-Mobilizing Second Messenger**
por: Tsuzuki, Takayoshi, et al.
Publicado: (2013)

A Novel Fluorescent Cell Membrane-permeable Caged Cyclic ADP-ribose Analogue
por: Yu, Pei-Lin, et al.
Publicado: (2012)

Vascular physiology of a Ca(2+) mobilizing second messenger - cyclic ADP - ribose
por: Zhang, Andrew Y, et al.
Publicado: (2006)

CD38/cADPR Signaling Pathway in Airway Disease: Regulatory Mechanisms
por: Deshpande, Deepak A., et al.
Publicado: (2018)

CD38/ADP-ribose/TRPM2-mediated nuclear Ca(2+) signaling is essential for hepatic gluconeogenesis in fasting and diabetes
por: Rah, So-Young, et al.
Publicado: (2023)

Proteome-wide identification of poly(ADP-ribose) binding proteins and poly(ADP-ribose)-associated protein complexes
por: Gagné, Jean-Philippe, et al.
Publicado: (2008)

Does Cyclic ADP-Ribose (cADPR) Activate the Non-selective Cation Channel TRPM2?
por: Fliegert, Ralf, et al.
Publicado: (2020)

Okamoto model for necrosis and its expansions, CD38-cyclic ADP-ribose signal system for intracellular Ca(2+) mobilization and Reg (Regenerating gene protein)-Reg receptor system for cell regeneration
por: OKAMOTO, Hiroshi, et al.
Publicado: (2021)

CD38 Structure-Based Inhibitor Design Using the N1-Cyclic Inosine 5′-Diphosphate Ribose Template
por: Moreau, Christelle, et al.
Publicado: (2013)

Potential biological role of poly (ADP-ribose) polymerase (PARP) in male gametes
por: Agarwal, Ashok, et al.
Publicado: (2009)

Poly(ADP-ribose): An organizer of cellular architecture
por: Leung, Anthony K.L.
Publicado: (2014)

Poly (ADP-ribose) in the pathogenesis of Parkinson's disease
por: Lee, Yunjong, et al.
Publicado: (2014)

RNA regulation by Poly(ADP-ribose) polymerases
por: Bock, Florian J., et al.
Publicado: (2015)

Oncogenic activity of poly (ADP-ribose) glycohydrolase
por: Marques, Maud, et al.
Publicado: (2018)

Mitotic functions of poly(ADP-ribose) polymerases
por: Slade, Dea
Publicado: (2019)

The Antiviral Activities of Poly-ADP-Ribose Polymerases
por: Malgras, Mathilde, et al.
Publicado: (2021)

ARH Family of ADP-Ribose-Acceptor Hydrolases
por: Ishiwata-Endo, Hiroko, et al.
Publicado: (2022)

Mutations of human DNA topoisomerase I at poly(ADP-ribose) binding sites: modulation of camptothecin activity by ADP-ribose polymers
por: Tesauro, Cinzia, et al.
Publicado: (2014)

Inhibition of Poly ADP-Ribose Glycohydrolase Sensitizes Ovarian Cancer Cells to Poly ADP-Ribose Polymerase Inhibitors and Platinum Agents
por: Matanes, Emad, et al.
Publicado: (2021)

Stability of centrosome numbers in poly(ADP-ribose) polymerase-1- and poly(ADP-ribose) glycohydrolase-deficient mouse ES cells
por: Ogino, Hideki, et al.
Publicado: (2004)

New Facets in the Regulation of Gene Expression by ADP-Ribosylation and Poly(ADP-ribose) Polymerases
por: Ryu, Keun Woo, et al.
Publicado: (2015)

Engineering Af1521 improves ADP-ribose binding and identification of ADP-ribosylated proteins
por: Nowak, Kathrin, et al.
Publicado: (2020)

Selective monitoring of the protein-free ADP-ribose released by ADP-ribosylation reversal enzymes
por: Kasson, Samuel, et al.
Publicado: (2021)

Molecular Insights into Poly(ADP-ribose) Recognition and Processing
por: Žaja, Roko, et al.
Publicado: (2012)

Poly(ADP-ribose) polymerase inhibitors in Ewing sarcoma
por: Vormoor, Britta, et al.
Publicado: (2014)

The Sound of Silence: RNAi in Poly (ADP-Ribose) Research
por: Blenn, Christian, et al.
Publicado: (2012)

Role of poly(ADP-ribose) polymerases in male reproduction
por: Celik-Ozenci, Ciler, et al.
Publicado: (2013)

Cannot write session to /tmp/vufind_sessions/sess_cke61vr64ceveocbcb2n143okb