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Global tests of P-values for multifactor dimensionality reduction models in selection of optimal number of target genes
BACKGROUND: Multifactor Dimensionality Reduction (MDR) is a popular and successful data mining method developed to characterize and detect nonlinear complex gene-gene interactions (epistasis) that are associated with disease susceptibility. Because MDR uses a combinatorial search strategy to detect...
Autores principales: | Dai, Hongying, Bhandary, Madhusudan, Becker, Mara, Leeder, J Steven, Gaedigk, Roger, Motsinger-Reif, Alison A |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508622/ https://www.ncbi.nlm.nih.gov/pubmed/22616673 http://dx.doi.org/10.1186/1756-0381-5-3 |
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