cFos Mediates cAMP-Dependent Generation of ROS and Rescue of Maturation Program in Retinoid-Resistant Acute Promyelocytic Leukemia Cell Line NB4-LR1

A determining role has been assigned to cAMP in the signaling pathways that relieve resistance to anti-leukemia differentiation therapy. However, the underlying mechanisms have not been elucidated yet. Here, we identify cFos as a critical cAMP effector, able to regulate the re-expression and splicin...

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Detalles Bibliográficos
Autores principales: Carrier, Jean-Luc, Javadi, Pasha, Bourrier, Emilie, Camus, Céline, Ségal-Bendirdjian, Evelyne, Karniguian, Aïda
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508928/
https://www.ncbi.nlm.nih.gov/pubmed/23209736
http://dx.doi.org/10.1371/journal.pone.0050408

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508928/
https://www.ncbi.nlm.nih.gov/pubmed/23209736
http://dx.doi.org/10.1371/journal.pone.0050408

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