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KRAS Mutation Is a Predictor of Oxaliplatin Sensitivity in Colon Cancer Cells
Molecular biomarkers to determine the effectiveness of targeted therapies in cancer treatment have been widely adopted in colorectal cancer (CRC), but those to predict chemotherapy sensitivity remain poorly defined. We tested our hypothesis that KRAS mutation may be a predictor of oxaliplatin sensit...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3508995/ https://www.ncbi.nlm.nih.gov/pubmed/23209813 http://dx.doi.org/10.1371/journal.pone.0050701 |