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Non-Synonymous Polymorphisms in the FCN1 Gene Determine Ligand-Binding Ability and Serum Levels of M-Ficolin
BACKGROUND: The innate immune system encompasses various recognition molecules able to sense both exogenous and endogenous danger signals arising from pathogens or damaged host cells. One such pattern-recognition molecule is M-ficolin, which is capable of activating the complement system through the...
Autores principales: | Ammitzbøll, Christian Gytz, Kjær, Troels Rønn, Steffensen, Rudi, Stengaard-Pedersen, Kristian, Nielsen, Hans Jørgen, Thiel, Steffen, Bøgsted, Martin, Jensenius, Jens Christian |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509001/ https://www.ncbi.nlm.nih.gov/pubmed/23209787 http://dx.doi.org/10.1371/journal.pone.0050585 |
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