Functional characterization of the matrix metalloproteinase-1 cigarette smoke-responsive region and association with the lung health study

BACKGROUND: Prior studies have demonstrated that the distal 1.5 kb of the MMP-1 promoter is fundamental in directing the induction of the MMP-1 gene by cigarette smoke. METHODS: To characterize the genetic variants in the MMP-1 cigarette smoke-responsive element, deep re-sequencing of this element w...

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Detalles Bibliográficos
Autores principales: Wallace, Alison M, Mercer, Becky A, He, Jianqing, Foronjy, Robert F, Accili, Domenico, Sandford, Andrew J, Paré, Peter D, D’Armiento, Jeanine M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2012
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509005/
https://www.ncbi.nlm.nih.gov/pubmed/22992122
http://dx.doi.org/10.1186/1465-9921-13-79

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