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Role of TLR4/NADPH oxidase/ROS-activated p38 MAPK in VCAM-1 expression induced by lipopolysaccharide in human renal mesangial cells

BACKGROUND: In bacteria-induced glomerulonephritis, Toll-like receptor 4 (TLR4) activation by lipopolysaccharide (LPS, a key component of the outer membranes of Gram-negative bacteria) can increase oxidative stress and the expression of vascular cell adhesion molecule-1 (VCAM-1), which recruits leuk...

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Detalles Bibliográficos
Autores principales:	Lee, I-Ta, Shih, Ruey-Horng, Lin, Chih-Chung, Chen, Jung-Tsan, Yang, Chuen-Mao
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2012
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509033/ https://www.ncbi.nlm.nih.gov/pubmed/23153039 http://dx.doi.org/10.1186/1478-811X-10-33

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