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Programmatic features of aging originating in development: aging mechanisms beyond molecular damage?

The idea that aging follows a predetermined sequence of events, a program, has been discredited by most contemporary authors. Instead, aging is largely thought to occur due to the accumulation of various forms of molecular damage. Recent work employing functional genomics now suggests that, indeed,...

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Detalles Bibliográficos
Autor principal: de Magalhães, João Pedro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Federation of American Societies for Experimental Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509060/
https://www.ncbi.nlm.nih.gov/pubmed/22964300
http://dx.doi.org/10.1096/fj.12-210872