Parental Diabetes: The Akita Mouse as a Model of the Effects of Maternal and Paternal Hyperglycemia in Wildtype Offspring

AIM/HYPOTHESIS: Maternal diabetes and high-fat feeding during pregnancy have been linked to later life outcomes in offspring. To investigate the effects of both maternal and paternal hyperglycemia on offspring phenotypes, we utilized an autosomal dominant mouse model of diabetes (hypoinsulinemic hyp...

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Detalles Bibliográficos
Autores principales: Grasemann, Corinna, Devlin, Maureen J., Rzeczkowska, Paulina A., Herrmann, Ralf, Horsthemke, Bernhard, Hauffa, Berthold P., Grynpas, Marc, Alm, Christina, Bouxsein, Mary L., Palmert, Mark R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509145/
https://www.ncbi.nlm.nih.gov/pubmed/23209676
http://dx.doi.org/10.1371/journal.pone.0050210

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