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Oncolytic measles virus strains have significant antitumor activity against glioma stem cells

Glioblastoma (GBM) is the most common primary brain tumor in adults and has a dismal prognosis despite multimodality treatment. Given the resistance of glioma stem cells (GSC) to chemotherapy and radiation therapy, their eradication could prevent tumor recurrence. We sought to evaluate the antitumor...

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Detalles Bibliográficos
Autores principales: Allen, Cory, Opyrchal, Mateusz, Aderca, Ileana, Schroeder, Mark A., Sarkaria, Jann N., Domingo, Evidio, Federspiel, Mark J., Galanis, Evanthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509233/
https://www.ncbi.nlm.nih.gov/pubmed/22914495
http://dx.doi.org/10.1038/gt.2012.62