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A Quantitative Assay for Assessing the Effects of DNA Lesions on Transcription

Most mammalian cells in nature are quiescent but actively transcribing mRNA for normal physiological processes; thus, it is important to investigate how endogenous and exogenous DNA damage compromises transcription in cells. Here we described a novel competitive transcription and adduct bypass (CTAB...

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Detalles Bibliográficos
Autores principales:	You, Changjun, Dai, Xiaoxia, Yuan, Bifeng, Wang, Jin, Wang, Jianshuang, Brooks, Philip J., Niedernhofer, Laura J., Wang, Yinsheng
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509257/ https://www.ncbi.nlm.nih.gov/pubmed/22902614 http://dx.doi.org/10.1038/nchembio.1046

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