Cargando…

Regulatory T Cells in HIV Infection: Can Immunotherapy Regulate the Regulator?

Regulatory T cells (Tregs) have a dominant role in self-tolerance and control of autoimmune diseases. These cells also play a pivotal role in chronic viral infections and cancer by limiting immune activation and specific immune response. The role of Tregs in HIV pathogenesis remains poorly understoo...

Descripción completa

Detalles Bibliográficos
Autores principales:	Jenabian, Mohammad-Ali, Ancuta, Petronela, Gilmore, Norbert, Routy, Jean-Pierre
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi Publishing Corporation 2012
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509372/ https://www.ncbi.nlm.nih.gov/pubmed/23251223 http://dx.doi.org/10.1155/2012/908314

Ejemplares similares

IDO-induced immunosuppressive tryptophan catabolism following primary HIV infection
por: Jenabian, Mohammad-Ali, et al.
Publicado: (2014)

Immune Suppression by Myeloid Cells in HIV Infection: New Targets for Immunotherapy
por: Mehraj, Vikram, et al.
Publicado: (2014)

Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers
por: Jenabian, Mohammad-Ali, et al.
Publicado: (2013)

Correction: Distinct Tryptophan Catabolism and Th17/Treg Balance in HIV Progressors and Elite Controllers
por: Jenabian, Mohammad-Ali, et al.
Publicado: (2014)

Interleukin-1β Triggers p53-Mediated Downmodulation of CCR5 and HIV-1 Entry in Macrophages through MicroRNAs 103 and 107
por: Lodge, Robert, et al.
Publicado: (2020)

Transcriptional profiling reveals molecular signatures associated with HIV permissiveness in Th1Th17 cells and identifies Peroxisome Proliferator-Activated Receptor Gamma as an intrinsic negative regulator of viral replication
por: Bernier, Annie, et al.
Publicado: (2013)

Impaired Th17 polarization of phenotypically naive CD4(+) T-cells during chronic HIV-1 infection and potential restoration with early ART
por: DaFonseca, Sandrina, et al.
Publicado: (2015)

The Biology of Monocytes and Dendritic Cells: Contribution to HIV Pathogenesis
por: Wacleche, Vanessa Sue, et al.
Publicado: (2018)

Dynamics and epigenetic signature of regulatory T-cells following antiretroviral therapy initiation in acute HIV infection
por: Yero, Alexis, et al.
Publicado: (2021)

HIV persistence in mucosal CD4(+) T cells within the lungs of adults receiving long-term suppressive antiretroviral therapy
por: Costiniuk, Cecilia T., et al.
Publicado: (2018)

The Th17 Lineage: From Barrier Surfaces Homeostasis to Autoimmunity, Cancer, and HIV-1 Pathogenesis
por: Wacleche, Vanessa Sue, et al.
Publicado: (2017)

New insights into the heterogeneity of Th17 subsets contributing to HIV-1 persistence during antiretroviral therapy
por: Wacleche, Vanessa Sue, et al.
Publicado: (2016)

Editorial: Modulation of the adaptive immune responses and chronicity of infections with enveloped viruses
por: Said, Elias A., et al.
Publicado: (2023)

Phylogenetic analysis of HIV-1 archived DNA in blood and gut-associated lymphoid tissue in two patients under antiretroviral therapy
por: Recordon-Pinson, Patricia, et al.
Publicado: (2021)

Regulatory T Cells Negatively Affect IL-2 Production of Effector T Cells through CD39/Adenosine Pathway in HIV Infection
por: Jenabian, Mohammad-Ali, et al.
Publicado: (2013)

Liver fibrosis is strongly associated with an enhanced level of immunosuppressive tryptophan catabolism independently of HCV viremia in ART-treated HIV/HCV co-infected patients
por: Jenabian, Mohammad-Ali, et al.
Publicado: (2014)

HIV and the Gut Microbiota, Partners in Crime: Breaking the Vicious Cycle to Unearth New Therapeutic Targets
por: Vyboh, Kishanda, et al.
Publicado: (2015)

FoxP3(+) CD8 T-cells in acute HIV infection and following early antiretroviral therapy initiation
por: Yero, Alexis, et al.
Publicado: (2022)

The Colocalization Potential of HIV-Specific CD8(+) and CD4(+) T-Cells is Mediated by Integrin β7 but Not CCR6 and Regulated by Retinoic Acid
por: Wacleche, Vanessa Sue, et al.
Publicado: (2012)

Down-Regulation of CTLA-4 by HIV-1 Nef Protein
por: El-Far, Mohamed, et al.
Publicado: (2013)

Identification of novel HIV-1 dependency factors in primary CCR4(+)CCR6(+)Th17 cells via a genome-wide transcriptional approach
por: Cleret-Buhot, Aurélie, et al.
Publicado: (2015)

HIV induces production of IL-18 from intestinal epithelial cells that increases intestinal permeability and microbial translocation
por: Allam, Ossama, et al.
Publicado: (2018)

Th17 cell master transcription factor RORC2 regulates HIV-1 gene expression and viral outgrowth
por: Wiche Salinas, Tomas Raul, et al.
Publicado: (2021)

Impact of in vitro HIV infection on human thymic regulatory T cell differentiation
por: Swaminathan, Sharada, et al.
Publicado: (2023)

HIV Infection and Persistence in Pulmonary Mucosal Double Negative T Cells In Vivo
por: Meziane, Oussama, et al.
Publicado: (2020)

Diurnal Variation of Plasma Extracellular Vesicle Is Disrupted in People Living with HIV
por: Bazié, Wilfried Wenceslas, et al.
Publicado: (2021)

Improving HIV Outgrowth by Optimizing Cell-Culture Conditions and Supplementing With all-trans Retinoic Acid
por: Zhang, Yuwei, et al.
Publicado: (2020)

The plasma levels of soluble ST2 as a marker of gut mucosal damage in early HIV infection
por: Mehraj, Vikram, et al.
Publicado: (2016)

Identification of aryl hydrocarbon receptor as a barrier to HIV-1 infection and outgrowth in CD4(+) T cells
por: Chatterjee, Debashree, et al.
Publicado: (2023)

The role of extended-release niacin on immune activation and neurocognition in HIV-infected patients treated with antiretroviral therapy – CTN PT006: study protocol for a randomized controlled trial
por: Lebouché, Bertrand, et al.
Publicado: (2014)

The grace of aging with ART: Ex vivo dendritic cell-based immunotherapy restores HIV-specific functional CD8(+) T-cells
por: Mehraj, Vikram, et al.
Publicado: (2022)

Translational research at acute HIV Infection
por: Routy, Jean Pierre
Publicado: (2010)

Effect of metformin on the size of the HIV reservoir in non-diabetic ART-treated individuals: single-arm non-randomised Lilac pilot study protocol
por: Routy, Jean-Pierre, et al.
Publicado: (2019)

Digoxin reveals a functional connection between HIV-1 integration preference and T-cell activation
por: Zhyvoloup, Alexander, et al.
Publicado: (2017)

The evaluation of risk-benefit ratio for gut tissue sampling in HIV cure research
por: Mehraj, Vikram, et al.
Publicado: (2017)

Nasal Nitric Oxide Levels in HIV Infection: A Cross-Sectional Study
por: Costiniuk, Cecilia T., et al.
Publicado: (2018)

Elevated Abundance, Size, and MicroRNA Content of Plasma Extracellular Vesicles in Viremic HIV-1+ Patients: Correlations With Known Markers of Disease Progression
por: Hubert, Audrey, et al.
Publicado: (2015)

HIV persists in CCR6(+)CD4(+) T cells from colon and blood during antiretroviral therapy
por: Gosselin, Annie, et al.
Publicado: (2017)

Early ART reduces viral seeding and innate immunity in liver and lungs of SIV-infected macaques
por: Clain, Julien A., et al.
Publicado: (2023)

Influence of Hepatitis C Virus Sustained Virological Response on Immunosuppressive Tryptophan Catabolism in ART-Treated HIV/HCV Coinfected Patients
por: Jenabian, Mohammad-Ali, et al.
Publicado: (2016)

Cannot write session to /tmp/vufind_sessions/sess_e03676hpt07rdfjkbs04i4o03l