Cargando…

BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients

Background. The “red complex” microorganisms, namely, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia are considered as potential pathogens causing HIV-associated periodontal diseases. Moreover, it has been recognized that an association exists between CD4+ T cell counts and...

Descripción completa

Detalles Bibliográficos
Autores principales: John, Cathy Nisha, Xavier Graham Stephen, Lawrence, Wilma Joyce Africa, Charlene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi Publishing Corporation 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509373/
https://www.ncbi.nlm.nih.gov/pubmed/23258979
http://dx.doi.org/10.1155/2012/157641
_version_ 1782251320897437696
author John, Cathy Nisha
Xavier Graham Stephen, Lawrence
Wilma Joyce Africa, Charlene
author_facet John, Cathy Nisha
Xavier Graham Stephen, Lawrence
Wilma Joyce Africa, Charlene
author_sort John, Cathy Nisha
collection PubMed
description Background. The “red complex” microorganisms, namely, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia are considered as potential pathogens causing HIV-associated periodontal diseases. Moreover, it has been recognized that an association exists between CD4+ T cell counts and periodontal disease progression. Objective. To establish whether CD4+ T cell counts or oral hygiene plays a greater role in producing BANA-positive results in HIV-associated periodontal disease. Materials and Methods. One hundred and twenty HIV-positive patients participated in the study, and their CD4+ T cell counts were obtained from their medical records. The six Ramfjord teeth were used for evaluating periodontal clinical indices and subgingival plaque sampling. BANA test was used for the detection and prevalence of the “red complex” bacteria in plaque samples. Results. A majority of 69.17% HIV-positive patients were BANA-positive. No significant associations were found between BANA and CD4+ T cell counts. A highly significant association was found between BANA with probing depth and clinical attachment level (P ≤ 0.0001) and between BANA and the use of interdental aids (P = 0.0168). Conclusion. HIV-associated periodontal diseases are strongly related to oral hygiene practices rather than the effect of CD4+ T cell counts, and the use of interdental aids was marked as a significant predictor of BANA-negative plaque samples.
format Online
Article
Text
id pubmed-3509373
institution National Center for Biotechnology Information
language English
publishDate 2012
publisher Hindawi Publishing Corporation
record_format MEDLINE/PubMed
spelling pubmed-35093732012-12-20 BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients John, Cathy Nisha Xavier Graham Stephen, Lawrence Wilma Joyce Africa, Charlene Int J Dent Research Article Background. The “red complex” microorganisms, namely, Porphyromonas gingivalis, Treponema denticola, and Tannerella forsythia are considered as potential pathogens causing HIV-associated periodontal diseases. Moreover, it has been recognized that an association exists between CD4+ T cell counts and periodontal disease progression. Objective. To establish whether CD4+ T cell counts or oral hygiene plays a greater role in producing BANA-positive results in HIV-associated periodontal disease. Materials and Methods. One hundred and twenty HIV-positive patients participated in the study, and their CD4+ T cell counts were obtained from their medical records. The six Ramfjord teeth were used for evaluating periodontal clinical indices and subgingival plaque sampling. BANA test was used for the detection and prevalence of the “red complex” bacteria in plaque samples. Results. A majority of 69.17% HIV-positive patients were BANA-positive. No significant associations were found between BANA and CD4+ T cell counts. A highly significant association was found between BANA with probing depth and clinical attachment level (P ≤ 0.0001) and between BANA and the use of interdental aids (P = 0.0168). Conclusion. HIV-associated periodontal diseases are strongly related to oral hygiene practices rather than the effect of CD4+ T cell counts, and the use of interdental aids was marked as a significant predictor of BANA-negative plaque samples. Hindawi Publishing Corporation 2012 2012-11-01 /pmc/articles/PMC3509373/ /pubmed/23258979 http://dx.doi.org/10.1155/2012/157641 Text en Copyright © 2012 Cathy Nisha John et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
John, Cathy Nisha
Xavier Graham Stephen, Lawrence
Wilma Joyce Africa, Charlene
BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients
title BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients
title_full BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients
title_fullStr BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients
title_full_unstemmed BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients
title_short BANA-Positive Plaque Samples Are Associated with Oral Hygiene Practices and Not CD4+ T Cell Counts in HIV-Positive Patients
title_sort bana-positive plaque samples are associated with oral hygiene practices and not cd4+ t cell counts in hiv-positive patients
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509373/
https://www.ncbi.nlm.nih.gov/pubmed/23258979
http://dx.doi.org/10.1155/2012/157641
work_keys_str_mv AT johncathynisha banapositiveplaquesamplesareassociatedwithoralhygienepracticesandnotcd4tcellcountsinhivpositivepatients
AT xaviergrahamstephenlawrence banapositiveplaquesamplesareassociatedwithoralhygienepracticesandnotcd4tcellcountsinhivpositivepatients
AT wilmajoyceafricacharlene banapositiveplaquesamplesareassociatedwithoralhygienepracticesandnotcd4tcellcountsinhivpositivepatients