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Wtip and Vangl2 are required for mitotic spindle orientation and cloaca morphogenesis
Defects in cilia and basal bodies function are linked to ciliopathies, which result in kidney cyst formation. Recently, cell division defects have been observed in cystic kidneys, but the underlying mechanisms of such defects remain unclear. Wtip is an LIM domain protein of the Ajuba/Zyxin family, b...
Autores principales: | Bubenshchikova, Ekaterina, Ichimura, Koichiro, Fukuyo, Yayoi, Powell, Rebecca, Hsu, Chaonan, Morrical, Stephen O., Sedor, John R., Sakai, Tatsuo, Obara, Tomoko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The Company of Biologists
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509438/ https://www.ncbi.nlm.nih.gov/pubmed/23213452 http://dx.doi.org/10.1242/bio.20121016 |
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