Identification of the ubiquitin ligase Triad1 as a regulator of endosomal transport

The ubiquitin system plays an important role in trafficking of signaling receptors from the plasma membrane to lysosomes. Triad1 is a ubiquitin ligase that catalyzes the formation of poly-ubiquitin chains linked via lysine-48 as well as lysine-63 residues. We show that depletion of Triad1 affects th...

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Detalles Bibliográficos
Autores principales: Hassink, Gerco, Slotman, Johan, Oorschot, Viola, Van Der Reijden, Bert A., Monteferrario, Davide, Noordermeer, Sylvie M., Van Kerkhof, Peter, Klumperman, Judith, Strous, Ger J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509441/
https://www.ncbi.nlm.nih.gov/pubmed/23213454
http://dx.doi.org/10.1242/bio.2012778

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