NuRD-dependent DNA methylation prevents ES cells from accessing a trophectoderm fate

Embryonic Stem (ES) cells are able to give rise to the three germ layers of the embryo but are prevented from contributing to the trophoblast. The molecular nature of this barrier between embryonic and trophectodermal cell fates is not clear, but is known to involve DNA methylation. Here we demonstr...

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Detalles Bibliográficos
Autores principales: Latos, Paulina A., Helliwell, Christine, Mosaku, Olukunbi, Dudzinska, Dominika A., Stubbs, Bryony, Berdasco, Maria, Esteller, Manel, Hendrich, Brian
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Company of Biologists 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509455/
https://www.ncbi.nlm.nih.gov/pubmed/23213424
http://dx.doi.org/10.1242/bio.2012513

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509455/
https://www.ncbi.nlm.nih.gov/pubmed/23213424
http://dx.doi.org/10.1242/bio.2012513

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