Induction of Apoptosis, G(0)/G(1) Phase Arrest and Microtubule Disassembly in K562 Leukemia Cells by Mere15, a Novel Polypeptide from Meretrix meretrix Linnaeus

Mere15 is a novel polypeptide from Meretrix meretrix Linnaeus with cytotoxicity in solid cancer cells. In this study, we investigated its activity on human K562 chronic myelogenous leukemia cells. Mere15 inhibited the growth of K562 cells with IC(50) values of 38.2 μg/mL. Mere15 also caused concentr...

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Detalles Bibliográficos
Autores principales: Liu, Ming, Zhao, Xiangzhong, Zhao, Jin, Xiao, Lin, Liu, Haizhou, Wang, Cuicui, Cheng, Linyou, Wu, Ning, Lin, Xiukun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509538/
https://www.ncbi.nlm.nih.gov/pubmed/23203280
http://dx.doi.org/10.3390/md10112596

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509538/
https://www.ncbi.nlm.nih.gov/pubmed/23203280
http://dx.doi.org/10.3390/md10112596

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