New Triterpenoids with Cytotoxic Activity from Actinidia Valvata

Two new triterpenoids, 30-O-β-d-glucopyranosyloxy-2α,3α,24-trihydroxyurs-12, 18-diene-28-oic acid O-β-d-glucopyranosyl ester (1) and 2α,3β,3,30-tetrahydroxyurs-12, 18-diene-28-oic acid O-β-d-glucopyranosyl ester (2) were isolated from roots of Actinidia valvata Dunn. Their structures were elucidated...

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Detalles Bibliográficos
Autores principales: Qu, Li-Ping, Zheng, Guo-Yin, Su, Yong-Hua, Zhang, Hui-Qing, Yang, Yan-Long, Xin, Hai-Liang, Ling, Chang-Quan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Molecular Diversity Preservation International (MDPI) 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509614/
https://www.ncbi.nlm.nih.gov/pubmed/23203098
http://dx.doi.org/10.3390/ijms131114865
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author Qu, Li-Ping
Zheng, Guo-Yin
Su, Yong-Hua
Zhang, Hui-Qing
Yang, Yan-Long
Xin, Hai-Liang
Ling, Chang-Quan
author_facet Qu, Li-Ping
Zheng, Guo-Yin
Su, Yong-Hua
Zhang, Hui-Qing
Yang, Yan-Long
Xin, Hai-Liang
Ling, Chang-Quan
author_sort Qu, Li-Ping
collection PubMed
description Two new triterpenoids, 30-O-β-d-glucopyranosyloxy-2α,3α,24-trihydroxyurs-12, 18-diene-28-oic acid O-β-d-glucopyranosyl ester (1) and 2α,3β,3,30-tetrahydroxyurs-12, 18-diene-28-oic acid O-β-d-glucopyranosyl ester (2) were isolated from roots of Actinidia valvata Dunn. Their structures were elucidated by means of extensive spectroscopic studies. Both these two new compounds showed moderate cytotoxic activity in vitro against BEL-7402 and SMMC-7721 tumor cell line.
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spelling pubmed-35096142013-01-09 New Triterpenoids with Cytotoxic Activity from Actinidia Valvata Qu, Li-Ping Zheng, Guo-Yin Su, Yong-Hua Zhang, Hui-Qing Yang, Yan-Long Xin, Hai-Liang Ling, Chang-Quan Int J Mol Sci Article Two new triterpenoids, 30-O-β-d-glucopyranosyloxy-2α,3α,24-trihydroxyurs-12, 18-diene-28-oic acid O-β-d-glucopyranosyl ester (1) and 2α,3β,3,30-tetrahydroxyurs-12, 18-diene-28-oic acid O-β-d-glucopyranosyl ester (2) were isolated from roots of Actinidia valvata Dunn. Their structures were elucidated by means of extensive spectroscopic studies. Both these two new compounds showed moderate cytotoxic activity in vitro against BEL-7402 and SMMC-7721 tumor cell line. Molecular Diversity Preservation International (MDPI) 2012-11-13 /pmc/articles/PMC3509614/ /pubmed/23203098 http://dx.doi.org/10.3390/ijms131114865 Text en © 2012 by the authors; licensee Molecular Diversity Preservation International, Basel, Switzerland. http://creativecommons.org/licenses/by/3.0 This article is an open-access article distributed under the terms and conditions of the Creative Commons Attribution license (http://creativecommons.org/licenses/by/3.0).
spellingShingle Article
Qu, Li-Ping
Zheng, Guo-Yin
Su, Yong-Hua
Zhang, Hui-Qing
Yang, Yan-Long
Xin, Hai-Liang
Ling, Chang-Quan
New Triterpenoids with Cytotoxic Activity from Actinidia Valvata
title New Triterpenoids with Cytotoxic Activity from Actinidia Valvata
title_full New Triterpenoids with Cytotoxic Activity from Actinidia Valvata
title_fullStr New Triterpenoids with Cytotoxic Activity from Actinidia Valvata
title_full_unstemmed New Triterpenoids with Cytotoxic Activity from Actinidia Valvata
title_short New Triterpenoids with Cytotoxic Activity from Actinidia Valvata
title_sort new triterpenoids with cytotoxic activity from actinidia valvata
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509614/
https://www.ncbi.nlm.nih.gov/pubmed/23203098
http://dx.doi.org/10.3390/ijms131114865
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