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Mutations Associated with Functional Disorder of Xanthine Oxidoreductase and Hereditary Xanthinuria in Humans

Xanthine oxidoreductase (XOR) catalyzes the conversion of hypoxanthine to xanthine and xanthine to uric acid with concomitant reduction of either NAD(+) or O(2). The enzyme is a target of drugs to treat hyperuricemia, gout and reactive oxygen-related diseases. Human diseases associated with genetica...

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Detalles Bibliográficos
Autores principales:	Ichida, Kimiyoshi, Amaya, Yoshihiro, Okamoto, Ken, Nishino, Takeshi
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Molecular Diversity Preservation International (MDPI) 2012
Materias:	Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509653/ https://www.ncbi.nlm.nih.gov/pubmed/23203137 http://dx.doi.org/10.3390/ijms131115475

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