How much of Virus-Specific CD8 T Cell Reactivity is Detected with a Peptide Pool when Compared to Individual Peptides?

Immune monitoring of T cell responses increasingly relies on the use of peptide pools. Peptides, when restricted by the same HLA allele, and presented from within the same peptide pool, can compete for HLA binding sites. What impact such competition has on functional T cell stimulation, however, is...

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Detalles Bibliográficos
Autores principales: Zhang, Wenji, Moldovan, Ioana, Targoni, Oleg S., Subbramanian, Ramu A., Lehmann, Paul V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509665/
https://www.ncbi.nlm.nih.gov/pubmed/23202497
http://dx.doi.org/10.3390/v4112636

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