Safety and Immunogenicity of a Plant-Produced Recombinant Hemagglutinin-Based Influenza Vaccine (HAI-05) Derived from A/Indonesia/05/2005 (H5N1) Influenza Virus: A Phase 1 Randomized, Double-Blind, Placebo-Controlled, Dose-Escalation Study in Healthy Adults

Recently, we have reported [1,2] on a subunit influenza vaccine candidate based on the recombinant hemagglutinin protein from the A/Indonesia/05/2005 (H5N1) strain of influenza virus, produced it using ‘launch vector’-based transient expression technology in Nicotiana benthamiana, and demonstrated i...

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Detalles Bibliográficos
Autores principales: Chichester, Jessica A., Jones, R. Mark, Green, Brian J., Stow, Mark, Miao, Fudu, Moonsammy, George, Streatfield, Stephen J., Yusibov, Vidadi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2012
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3509691/
https://www.ncbi.nlm.nih.gov/pubmed/23202523
http://dx.doi.org/10.3390/v4113227

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