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Human Cdc14A regulates Wee1 stability by counteracting CDK-mediated phosphorylation
The activity of Cdk1–cyclin B1 mitotic complexes is regulated by the balance between the counteracting activities of Wee1/Myt1 kinases and Cdc25 phosphatases. These kinases and phosphatases must be strictly regulated to ensure proper mitotic timing. One masterpiece of this regulatory network is Cdk1...
Autores principales: | Ovejero, Sara, Ayala, Patricia, Bueno, Avelino, Sacristán, María P. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
The American Society for Cell Biology
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510014/ https://www.ncbi.nlm.nih.gov/pubmed/23051732 http://dx.doi.org/10.1091/mbc.E12-04-0260 |
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