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Human Cdc14A regulates Wee1 stability by counteracting CDK-mediated phosphorylation

The activity of Cdk1–cyclin B1 mitotic complexes is regulated by the balance between the counteracting activities of Wee1/Myt1 kinases and Cdc25 phosphatases. These kinases and phosphatases must be strictly regulated to ensure proper mitotic timing. One masterpiece of this regulatory network is Cdk1...

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Detalles Bibliográficos
Autores principales: Ovejero, Sara, Ayala, Patricia, Bueno, Avelino, Sacristán, María P.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The American Society for Cell Biology 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510014/
https://www.ncbi.nlm.nih.gov/pubmed/23051732
http://dx.doi.org/10.1091/mbc.E12-04-0260

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