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NMI mediates transcription-independent ARF regulation in response to cellular stresses

The ARF tumor suppressor is a product of the INK4a/ARF locus, which is frequently mutated in human cancer. The expression of ARF is up-regulated in response to certain types of DNA damage, oncogene activation, and interferon stimuli. Through interaction with the p53 negative regulator MDM2, ARF cont...

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Detalles Bibliográficos
Autores principales:	Li, Zengpeng, Hou, Jingjing, Sun, Li, Wen, Taoyong, Wang, Liqin, Zhao, Xinmeng, Xie, Qingqing, Zhang, Si Qing
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The American Society for Cell Biology 2012
Materias:	Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510024/ https://www.ncbi.nlm.nih.gov/pubmed/23034180 http://dx.doi.org/10.1091/mbc.E12-04-0304

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