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Zcchc11 Uridylates Mature miRNAs to Enhance Neonatal IGF-1 Expression, Growth, and Survival

The Zcchc11 enzyme is implicated in microRNA (miRNA) regulation. It can uridylate let-7 precursors to decrease quantities of the mature miRNA in embryonic stem cell lines, suggested to mediate stem cell maintenance. It can uridylate mature miR-26 to relieve silencing activity without impacting miRNA...

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Detalles Bibliográficos
Autores principales:	Jones, Matthew R., Blahna, Matthew T., Kozlowski, Elyse, Matsuura, Kori Y., Ferrari, Joseph D., Morris, Samantha A., Powers, John T., Daley, George Q., Quinton, Lee J., Mizgerd, Joseph P.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510031/ https://www.ncbi.nlm.nih.gov/pubmed/23209448 http://dx.doi.org/10.1371/journal.pgen.1003105

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