The Principal Genetic Determinants for Nasopharyngeal Carcinoma in China Involve the HLA Class I Antigen Recognition Groove

Nasopharyngeal carcinoma (NPC) is an epithelial malignancy facilitated by Epstein-Barr Virus infection. Here we resolve the major genetic influences for NPC incidence using a genome-wide association study (GWAS), independent cohort replication, and high-resolution molecular HLA class I gene typing i...

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Detalles Bibliográficos
Autores principales: Tang, Minzhong, Lautenberger, James A., Gao, Xiaojiang, Sezgin, Efe, Hendrickson, Sher L., Troyer, Jennifer L., David, Victor A., Guan, Li, Mcintosh, Carl E., Guo, Xiuchan, Zheng, Yuming, Liao, Jian, Deng, Hong, Malasky, Michael, Kessing, Bailey, Winkler, Cheryl A., Carrington, Mary, dé The, Guy, Zeng, Yi, O'Brien, Stephen J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510037/
https://www.ncbi.nlm.nih.gov/pubmed/23209447
http://dx.doi.org/10.1371/journal.pgen.1003103

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