Mutations in the Transcription Elongation Factor SPT5 Disrupt a Reporter for Dosage Compensation in Drosophila

In Drosophila, the MSL (Male Specific Lethal) complex up regulates transcription of active genes on the single male X-chromosome to equalize gene expression between sexes. One model argues that the MSL complex acts upon the elongation step of transcription rather than initiation. In an unbiased forw...

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Detalles Bibliográficos
Autores principales: Prabhakaran, Mahalakshmi, Kelley, Richard L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510053/
https://www.ncbi.nlm.nih.gov/pubmed/23209435
http://dx.doi.org/10.1371/journal.pgen.1003073

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