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Kinetics of Amyloid Aggregation: A Study of the GNNQQNY Prion Sequence
The small amyloid-forming GNNQQNY fragment of the prion sequence has been the subject of extensive experimental and numerical studies over the last few years. Using unbiased molecular dynamics with the OPEP coarse-grained potential, we focus here on the onset of aggregation in a 20-mer system. With...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Public Library of Science
2012
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510058/ https://www.ncbi.nlm.nih.gov/pubmed/23209391 http://dx.doi.org/10.1371/journal.pcbi.1002782 |