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Corticosteroid-Induced Immunosuppression Ultimately Does Not Compromise the Efficacy of Antibiotherapy in Murine Mycobacterium ulcerans Infection
BACKGROUND: Buruli ulcer (BU) is a necrotizing disease of the skin, subcutaneous tissue and bone caused by Mycobacterium ulcerans. It has been suggested that the immune response developed during the recommended rifampicin/streptomycin (RS) antibiotherapy is protective, contributing to bacterial clea...
Autores principales: | Martins, Teresa G., Trigo, Gabriela, Fraga, Alexandra G., Gama, José B., Longatto-Filho, Adhemar, Saraiva, Margarida, Silva, Manuel T., Castro, António G., Pedrosa, Jorge |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510087/ https://www.ncbi.nlm.nih.gov/pubmed/23209864 http://dx.doi.org/10.1371/journal.pntd.0001925 |
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