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Selective Infection of Antigen-Specific B Lymphocytes by Salmonella Mediates Bacterial Survival and Systemic Spreading of Infection
BACKGROUND: The bacterial pathogen Salmonella causes worldwide disease. A major route of intestinal entry involves M cells, providing access to B cell-rich Peyer’s Patches. Primary human B cells phagocytose Salmonella typhimurium upon recognition by the specific surface Ig receptor (BCR). As it is u...
Autores principales: | Souwer, Yuri, Griekspoor, Alexander, de Wit, Jelle, Martinoli, Chiara, Zagato, Elena, Janssen, Hans, Jorritsma, Tineke, Bar-Ephraïm, Yotam E., Rescigno, Maria, Neefjes, Jacques, van Ham, S. Marieke |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510171/ https://www.ncbi.nlm.nih.gov/pubmed/23209805 http://dx.doi.org/10.1371/journal.pone.0050667 |
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