Cargando…

Lack of Evidence for mtDNA as a Biomarker of Innate Immune Activation in HIV Infection

Many human immunodeficiency virus (HIV) infected individuals suffer from persistent immune activation. Chronic inflammation and immune dysregulation have been associated with an increased risk of age-related diseases even among patients on highly active antiretroviral therapy. The factors leading to...

Descripción completa

Detalles Bibliográficos
Autores principales:	Lauring, Adam S., Lee, Tzong-Hae, Martin, Jeffrey N., Hunt, Peter W., Deeks, Steven G., Busch, Michael
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510194/ https://www.ncbi.nlm.nih.gov/pubmed/23209754 http://dx.doi.org/10.1371/journal.pone.0050486

Ejemplares similares

Ancient mtDNA Genetic Variants Modulate mtDNA Transcription and Replication
por: Suissa, Sarit, et al.
Publicado: (2009)

In vivo methylation of mtDNA reveals the dynamics of protein–mtDNA interactions
por: Rebelo, Adriana P., et al.
Publicado: (2009)

Fumarate induces vesicular release of mtDNA to drive innate immunity
por: Zecchini, Vincent, et al.
Publicado: (2023)

Evidence for a Fourteenth mtDNA-Encoded Protein in the Female-Transmitted mtDNA of Marine Mussels (Bivalvia: Mytilidae)
por: Breton, Sophie, et al.
Publicado: (2011)

Where mtDNA is made
por: LeBrasseur, Nicole
Publicado: (2003)

Melanesian mtDNA Complexity
por: Friedlaender, Jonathan S., et al.
Publicado: (2007)

Healthy, mtDNA-mutation free mesoangioblasts from mtDNA patients qualify for autologous therapy
por: van Tienen, Florence, et al.
Publicado: (2019)

No Evidence of Neandertal mtDNA Contribution to Early Modern Humans
por: Serre, David, et al.
Publicado: (2004)

No evidence of extensive non-CpG methylation in mtDNA
por: Guitton, Romain, et al.
Publicado: (2022)

Origins and Evolution of the Etruscans’ mtDNA
por: Ghirotto, Silvia, et al.
Publicado: (2013)

mtDNA in the Pathogenesis of Cardiovascular Diseases
por: Wang, Lili, et al.
Publicado: (2021)

Linear mtDNA fragments and unusual mtDNA rearrangements associated with pathological deficiency of MGME1 exonuclease
por: Nicholls, Thomas J., et al.
Publicado: (2014)

Differences in Liver TFAM Binding to mtDNA and mtDNA Damage between Aged and Extremely Aged Rats
por: Chimienti, Guglielmina, et al.
Publicado: (2019)

Modulation of mtDNA copy number ameliorates the pathological consequences of a heteroplasmic mtDNA mutation in the mouse
por: Filograna, R., et al.
Publicado: (2019)

Increased TFAM binding to mtDNA damage hot spots is associated with mtDNA loss in aged rat heart
por: Chimienti, Guglielmina, et al.
Publicado: (2018)

Association of circulating MtDNA with CVD in hemodialysis patients and in vitro effect of exogenous MtDNA on cardiac microvascular inflammation
por: Fan, Zhen, et al.
Publicado: (2023)

Keeping mtDNA in Shape between Generations
por: Stewart, James B., et al.
Publicado: (2014)

MtDNA-maintenance defects: syndromes and genes
por: Viscomi, Carlo, et al.
Publicado: (2017)

The Early Peopling of the Philippines based on mtDNA
por: Arenas, Miguel, et al.
Publicado: (2020)

Evolving mtDNA populations within cells
por: Johnston, Iain G., et al.
Publicado: (2019)

Molecular Mechanisms of mtDNA-Mediated Inflammation
por: De Gaetano, Anna, et al.
Publicado: (2021)

Role of the mtDNA Mutations and Mitophagy in Inflammaging
por: Dabravolski, Siarhei A., et al.
Publicado: (2022)

Is the Dinoflagellate Amoebophrya Really Missing an mtDNA?
por: Kayal, Ehsan, et al.
Publicado: (2021)

Genetic Diversity in the mtDNA of Physarum polycephalum
por: Hammar, Freya, et al.
Publicado: (2023)

TFAM in mtDNA Homeostasis: Open Questions
por: Alexeyev, Mikhail
Publicado: (2023)

Mitochondrial DNA (mtDNA) haplotypes and dysfunctions in presbyacusis
por: MOSTAFA, H., et al.
Publicado: (2014)

ALS spinal neurons show varied and reduced mtDNA gene copy numbers and increased mtDNA gene deletions
por: Keeney, Paula M, et al.
Publicado: (2010)

Partial tandem duplication of mtDNA–tRNA(Phe) impairs mtDNA translation in late-onset mitochondrial myopathy
por: Arzuffi, Paola, et al.
Publicado: (2012)

Similar patterns of clonally expanded somatic mtDNA mutations in the colon of heterozygous mtDNA mutator mice and ageing humans
por: Baines, Holly L., et al.
Publicado: (2014)

A method for mutagenesis of mouse mtDNA and a resource of mouse mtDNA mutations for modeling human pathological conditions
por: Fayzulin, Rafik Z., et al.
Publicado: (2015)

mtDNA, Metastasis, and the Mitochondrial Unfolded Protein Response (UPR(mt))
por: Kenny, Timothy C., et al.
Publicado: (2017)

Mice lacking the mitochondrial exonuclease MGME1 accumulate mtDNA deletions without developing progeria
por: Matic, Stanka, et al.
Publicado: (2018)

Fusion of Wild-Type Mesoangioblasts with Myotubes of mtDNA Mutation Carriers Leads to a Proportional Reduction in mtDNA Mutation Load
por: Zelissen, Ruby, et al.
Publicado: (2023)

Mitochondrial Replication Assay (MIRA) for Efficient in situ Quantification of Nascent mtDNA and Protein Interactions with Nascent mtDNA (mitoSIRF)
por: Lozen, Macy, et al.
Publicado: (2023)

Mitochondrial Genome (mtDNA) Mutations that Generate Reactive Oxygen Species
por: Hahn, Anne, et al.
Publicado: (2019)

Absence of mtDNA mutations in leukocytes of CADASIL patients
por: Abu-Amero, Khaled K, et al.
Publicado: (2008)

External Contamination in Single Cell mtDNA Analysis
por: Yao, Yong-Gang, et al.
Publicado: (2007)

Possibility of selection against mtDNA mutations in tumors
por: Khaidakov, M, et al.
Publicado: (2005)

Coevolution of Drosophila melanogaster mtDNA and Wolbachia Genotypes
por: Ilinsky, Yury
Publicado: (2013)

Mitochondrial activity in gametes and transmission of viable mtDNA
por: Milani, Liliana, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_korgh1ctbm63tvnag7h7e3a1ju