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A Systemically-Administered Small Molecule Antagonist of CCR9 Acts as a Tissue-Selective Inhibitor of Lymphocyte Trafficking

A goal for developers of immunomodulatory drugs has long been a systemically administered small molecule that can selectively inhibit inflammation in specific tissues. The chemokine receptor CCR9 is an attractive target for this approach, as entry of T cells into the small intestine from blood requi...

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Detalles Bibliográficos
Autores principales:	Tubo, Noah J., Wurbel, Marc A., Charvat, Trevor T., Schall, Thomas J., Walters, Matthew J., Campbell, James J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2012
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510197/ https://www.ncbi.nlm.nih.gov/pubmed/23209760 http://dx.doi.org/10.1371/journal.pone.0050498

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