Role of Transmitted Gag CTL Polymorphisms in Defining Replicative Capacity and Early HIV-1 Pathogenesis

Initial studies of 88 transmission pairs in the Zambia Emory HIV Research Project cohort demonstrated that the number of transmitted HLA-B associated polymorphisms in Gag, but not Nef, was negatively correlated to set point viral load (VL) in the newly infected partners. These results suggested that...

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Detalles Bibliográficos
Autores principales: Prince, Jessica L., Claiborne, Daniel T., Carlson, Jonathan M., Schaefer, Malinda, Yu, Tianwei, Lahki, Shabir, Prentice, Heather A., Yue, Ling, Vishwanathan, Sundaram A., Kilembe, William, Goepfert, Paul, Price, Matthew A., Gilmour, Jill, Mulenga, Joseph, Farmer, Paul, Derdeyn, Cynthia A., Tang, Jiaming, Heckerman, David, Kaslow, Richard A., Allen, Susan A., Hunter, Eric
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2012
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510241/
https://www.ncbi.nlm.nih.gov/pubmed/23209412
http://dx.doi.org/10.1371/journal.ppat.1003041

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