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The Salmonella Kinase SteC Targets the MAP Kinase MEK to Regulate the Host Actin Cytoskeleton

After host cell entry, Salmonella replicate in membrane-bound compartments, which accumulate a dense meshwork of F-actin through the kinase activity of the Salmonella SPI-2 type III secretion effector SteC. We find that SteC promotes actin cytoskeleton reorganization by activating a signaling pathwa...

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Detalles Bibliográficos
Autores principales:	Odendall, Charlotte, Rolhion, Nathalie, Förster, Andreas, Poh, John, Lamont, Douglas J., Liu, Mei, Freemont, Paul S., Catling, Andrew D., Holden, David W.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Cell Press 2012
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510437/ https://www.ncbi.nlm.nih.gov/pubmed/23159055 http://dx.doi.org/10.1016/j.chom.2012.09.011

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