Cargando…

The CLC-5 2Cl(−)/H(+) exchange transporter in endosomal function and Dent's disease

CLC-5 plays a critical role in the process of endocytosis in the proximal tubule of the kidney and mutations that alter protein function are the cause of Dent's I disease. In this X-linked disorder impaired reabsorption results in the wasting of calcium and low molecular weight protein to the u...

Descripción completa

Detalles Bibliográficos
Autores principales: Lippiat, Jonathan D., Smith, Andrew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510460/
https://www.ncbi.nlm.nih.gov/pubmed/23226131
http://dx.doi.org/10.3389/fphys.2012.00449

Ejemplares similares