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The CLC-5 2Cl(−)/H(+) exchange transporter in endosomal function and Dent's disease
CLC-5 plays a critical role in the process of endocytosis in the proximal tubule of the kidney and mutations that alter protein function are the cause of Dent's I disease. In this X-linked disorder impaired reabsorption results in the wasting of calcium and low molecular weight protein to the u...
Autores principales: | Lippiat, Jonathan D., Smith, Andrew J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510460/ https://www.ncbi.nlm.nih.gov/pubmed/23226131 http://dx.doi.org/10.3389/fphys.2012.00449 |
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