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Age-dependent α-synuclein aggregation in the Microcebus murinus lemur primate

Since age-dependent deposition of Aβ-amyloid has been reported in the Microcebus murinus, we posited that this animal could as well be a model of age-related synucleinopathy. We characterized the distribution of Aβ-amyloid, α-synuclein and two of its modified forms in the brain of Microcebus murinus...

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Detalles Bibliográficos
Autores principales: Canron, Marie-Hélène, Perret, Martine, Vital, Anne, Bézard, Erwan, Dehay, Benjamin
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group 2012
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510464/
https://www.ncbi.nlm.nih.gov/pubmed/23205271
http://dx.doi.org/10.1038/srep00910