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Delineation of breast cancer cell hierarchy identifies the subset responsible for dormancy
The bone marrow (BM) is a major organ of breast cancer (BC) dormancy and a common source of BC resurgence. Gap junctional intercellular communication (GJIC) between BC cells (BCCs) and BM stroma facilitates dormancy. This study reports on a hierarchy of BCCs with the most immature subset (Oct4(hi)/C...
Autores principales: | Patel, Shyam A., Ramkissoon, Shakti H., Bryan, Margarette, Pliner, Lillian F., Dontu, Gabriela, Patel, Prem S., Amiri, Sohrab, Pine, Sharon R., Rameshwar, Pranela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group
2012
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510468/ https://www.ncbi.nlm.nih.gov/pubmed/23205268 http://dx.doi.org/10.1038/srep00906 |
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