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Persistent androgen receptor-mediated transcription in castration-resistant prostate cancer under androgen-deprived conditions

The androgen receptor (AR) is a ligand-inducible transcription factor that mediates androgen action in target tissues. Upon ligand binding, the AR binds to thousands of genomic loci and activates a cell-type specific gene program. Prostate cancer growth and progression depend on androgen-induced AR...

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Detalles Bibliográficos
Autores principales:	Decker, Keith F., Zheng, Dali, He, Yuhong, Bowman, Tamara, Edwards, John R., Jia, Li
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510497/ https://www.ncbi.nlm.nih.gov/pubmed/23019221 http://dx.doi.org/10.1093/nar/gks888

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