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The roles of WRN and BLM RecQ helicases in the Alternative Lengthening of Telomeres

Approximately 10% of all cancers, but a higher proportion of sarcomas, use the recombination-based alternative lengthening of telomeres (ALT) to maintain telomeres. Two RecQ helicase genes, BLM and WRN, play important roles in homologous recombination repair and they have been implicated in telomeri...

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Detalles Bibliográficos
Autores principales:	Mendez-Bermudez, Aaron, Hidalgo-Bravo, Alberto, Cotton, Victoria E., Gravani, Athanasia, Jeyapalan, Jennie N., Royle, Nicola J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Genome Integrity, Repair and Replication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510502/ https://www.ncbi.nlm.nih.gov/pubmed/22989712 http://dx.doi.org/10.1093/nar/gks862

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