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Estrogen-induced upregulation and 3′-UTR shortening of CDC6

3′-Untranslated region (UTR) shortening of mRNAs via alternative polyadenylation (APA) has important ramifications for gene expression. By using proximal APA sites and switching to shorter 3′-UTRs, proliferating cells avoid miRNA-mediated repression. Such APA and 3′-UTR shortening events may explain...

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Detalles Bibliográficos
Autores principales:	Akman, Begum H., Can, Tolga, Erson-Bensan, A. Elif
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2012
Materias:	Gene Regulation, Chromatin and Epigenetics
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510512/ https://www.ncbi.nlm.nih.gov/pubmed/22977174 http://dx.doi.org/10.1093/nar/gks855

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