Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature

Lipodystrophy is a clinical disorder characterized by maldistribution of body fat. Hyperinsulinemia, insulin resistance, and abnormalities of glucose homeostasis are commonly described among these patients. Hyperinsulinemia is also involved in the pathogenesis of polycystic ovarian syndrome, a condi...

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Autores principales: Pahuja, Isha, De, Prasanjit, Sharma, Neera, Kulshreshtha, Bindu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2012
Materias:
Case Report with Review of Literature
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510931/
https://www.ncbi.nlm.nih.gov/pubmed/23226657
http://dx.doi.org/10.4103/2230-8210.103031
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author Pahuja, Isha
De, Prasanjit
Sharma, Neera
Kulshreshtha, Bindu
author_facet Pahuja, Isha
De, Prasanjit
Sharma, Neera
Kulshreshtha, Bindu
author_sort Pahuja, Isha
collection PubMed
description Lipodystrophy is a clinical disorder characterized by maldistribution of body fat. Hyperinsulinemia, insulin resistance, and abnormalities of glucose homeostasis are commonly described among these patients. Hyperinsulinemia is also involved in the pathogenesis of polycystic ovarian syndrome, a condition, described rarely in patients with lipodystrophy. Here, we describe 2 females of partial lipodystrophy who presented with features of polycystic ovarian disease. Both had severe hyperinsulinemia and irregular periods, one had hyperandrogenism and hirsuitism while the other was non-hirsuite.
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spelling pubmed-35109312012-12-05 Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature Pahuja, Isha De, Prasanjit Sharma, Neera Kulshreshtha, Bindu Indian J Endocrinol Metab Case Report with Review of Literature Lipodystrophy is a clinical disorder characterized by maldistribution of body fat. Hyperinsulinemia, insulin resistance, and abnormalities of glucose homeostasis are commonly described among these patients. Hyperinsulinemia is also involved in the pathogenesis of polycystic ovarian syndrome, a condition, described rarely in patients with lipodystrophy. Here, we describe 2 females of partial lipodystrophy who presented with features of polycystic ovarian disease. Both had severe hyperinsulinemia and irregular periods, one had hyperandrogenism and hirsuitism while the other was non-hirsuite. Medknow Publications & Media Pvt Ltd 2012 /pmc/articles/PMC3510931/ /pubmed/23226657 http://dx.doi.org/10.4103/2230-8210.103031 Text en Copyright: © Indian Journal of Endocrinology and Metabolism http://creativecommons.org/licenses/by-nc-sa/3.0 This is an open-access article distributed under the terms of the Creative Commons Attribution-Noncommercial-Share Alike 3.0 Unported, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Report with Review of Literature
Pahuja, Isha
De, Prasanjit
Sharma, Neera
Kulshreshtha, Bindu
Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature
title Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature
title_full Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature
title_fullStr Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature
title_full_unstemmed Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature
title_short Polycystic ovarian syndrome in patients with lipodystrophy: Report of 2 cases with review of literature
title_sort polycystic ovarian syndrome in patients with lipodystrophy: report of 2 cases with review of literature
topic Case Report with Review of Literature
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC3510931/
https://www.ncbi.nlm.nih.gov/pubmed/23226657
http://dx.doi.org/10.4103/2230-8210.103031
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